2'-deoxy-2'-fluoro-2'-C-methylcytidine

Product Name: 2'-deoxy-2'-fluoro-2'-C-methylcytidine
CAS No.: 817204-33-4
Chemical Name: 2'-deoxy-2'-fluoro-2'-C-methylcytidine
Synonyms: ethyl 4-broMo-1-Methyl-1H-pyrrole-2-carboxylate;PSI 6130;R 1656;CS-1995;PSI-6130;PSI 6130;Sofosbuvir Impurity 121;PSI-6130;R 1656;PSI 6130;2'-Deoxy-2'-F-2'-C-methylcytidine;2'-deoxy-2'-Fluoro-2'-methylcytidine;2'-deoxy-2'-fluoro-2'-C-methylcytidin
CBNumber: CB22525888
Molecular Formula: C10H14FN3O4
Formula Weight: 259.23
MOL File: 817204-33-4.mol

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2'-deoxy-2'-fluoro-2'-C-methylcytidine Property

Melting point:: 216-218℃
Boiling point:: 482.4±55.0 °C(Predicted)
Density: 1.67
storage temp.: Hygroscopic, -20°C Freezer, Under inert atmosphere
solubility: Methanol (Slightly), Water (Slightly)
pka: 12.86±0.70(Predicted)
form: Solid
color: White to Light Brown
Stability:: Hygroscopic

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Cayman Chemical

Product number: 13575
Product name: PSI-6130
Packaging: 1mg
Price: $93
Updated: 2024/03/01

Cayman Chemical

Product number: 13575
Product name: PSI-6130
Packaging: 5mg
Price: $321
Updated: 2024/03/01

TRC

Product number: P839680
Product name: PSI6130
Packaging: 25mg
Price: $640
Updated: 2021/12/16

Matrix Scientific

Product number: 097930
Product name: 4-Amino-1-((2R,3R,4R,5R)-3-fluoro-4-hydroxy-5-(hydroxymethyl)-3-methyltetrahydrofuran-2-yl)pyrimidin-2(1H)-one
Purity: 95+%
Packaging: 1g
Price: $685
Updated: 2021/12/16

Biorbyt Ltd

Product number: orb146167
Product name: PSI6130
Purity: >99%
Packaging: 1g
Price: $765
Updated: 2021/12/16

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2'-deoxy-2'-fluoro-2'-C-methylcytidine Chemical Properties,Usage,Production

Description

PSI-6130 is a nucleoside inhibitor of the NS5B RNA polymerase of hepatitis C virus (HCV; K_i = 4.3 μM). It inhibits HCV genotype 1b (GT-1b) Con1 and GT-1a H77 viral replication in Huh7 replicon cells using a luciferase-based assay (EC₅₀s = 0.51 and 0.30 μM, respectively). PSI-6130 also inhibits replication of HCV GT-1b and GT-1a replicons from clinical isolates, with EC₅₀ values ranging from 0.60 to 1.41 μM, and 0.20 to 0.43 μM, respectively, in the same assay. It has little or no activity against West Nile Virus (WNV), Dengue type 2 virus (DV), human immunodeficiency virus (HIV), or hepatitis B virus (HBV; EC₉₀s = 46.3, >100, >100, and >10 μM, respectively).

Uses

PSI-6130 is an experimental treatment for hepatitis C. PSI-6130 is a member of a class of antiviral drugs known as nucleoside polymerase inhibitors. PSI-6130 inhibits the hepatitis C virus RNA dependant RNA polymerase called NS5B.

target

Hepatitis C Virus Nucleoside

2'-deoxy-2'-fluoro-2'-C-methylcytidine Preparation Products And Raw materials

Raw materials

Preparation Products

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2'-deoxy-2'-fluoro-2'-C-methylcytidine Suppliers

China 108 India 1 United Kingdom 1 United States 14 Global 124

AdooQ BioScience, LLC

Tel: +1 (866) 930-6790
Fax: +1 (866) 333-9607
Email: info@adooq.com
Country: United States
ProdList: 2784
Advantage: 58

Musechem

Tel: +1-800-259-7612
Fax: +1-800-259-7612
Email: info@musechem.com
Country: United States
ProdList: 4662
Advantage: 60

InvivoChem

Tel: +1-708-310-1919 +1-13798911105
Fax: 708-557-7486
Email: sales@invivochem.cn
Country: United States
ProdList: 6393
Advantage: 58

Cckinase, Inc.

Tel: +1 (732)236-3202
Email: sales@cckinase.com
Country: United States
ProdList: 2738
Advantage: 58

BOC Sciences

Tel: +1-631-485-4226
Fax: 1-631-614-7828
Email: inquiry@bocsci.com
Country: United States
ProdList: 19553
Advantage: 58

Aladdin Scientific

Tel: +1-833-552-7181
Email: sales@aladdinsci.com
Country: United States
ProdList: 57511
Advantage: 58

TargetMol Chemicals Inc.

Tel: +1-781-999-5354
Email: support@targetmol.com
Country: United States
ProdList: 19973
Advantage: 58

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View Lastest Price from 2'-deoxy-2'-fluoro-2'-C-methylcytidine manufacturers

Henan Fengda Chemical Co., Ltd

Product: 2'-deoxy-2'-fluoro-2'-C-methylcytidine 817204-33-4
Price: US $5.00-0.10/KG
Min. Order: 1KG
Purity: 99%
Supply Ability: g-kg-tons, free sample is available
Release date: 2024-03-22

Career Henan Chemical Co

Product: 2'-deoxy-2'-fluoro-2'-C-methylcytidine 817204-33-4
Price: US $5.00/KG
Min. Order: 1KG
Purity: 99%
Supply Ability: 1ton
Release date: 2019-08-05

817204-33-4, 2'-deoxy-2'-fluoro-2'-C-methylcytidineRelated Search:

(3R,4R,5R)-3-fluoro-4-hydroxy-5-(hydroxyMethyl)-3-Methyl-dihydrofuran-2(3H)-one 4-Pyridinecarboxamide, 3-chloro-N-methyl- 3-Pyridinecarboxamide, 4-chloro-N-methyl- ((2R,3S,4S)-3-(benzoyloxy)-4-fluoro-4-Methyl-5-oxotetrahydrofuran-2-yl)Methyl benzoate N4-Benzoylcytosine (2R)-2-Deoxy-2-fluoro-2-Methyl-D-erythro-pentonic acid-g-lactone 3,5-bis(4-chlorobenzoate) 2'-C-Methyl-, 2',3',5'-tribenzoateuridine 3-Pyridinecarboxamide, 5-chloro-N-methyl- 2'-deoxy-2'-fluoro-2'-C-methyluridine HUMAN MDC (CCL22) 3-Aminobenzotrifluoride

(2'R)-2'-deoxy-2'-fluoro-2'-methyl-Cytidine

PSI-6130;R 1656;PSI 6130

4-Amino-1-((2R,3R,4R,5R)-3-fluoro-4-hydroxy-5-(hydroxymethyl)-3-methyltetrahydrofuran-2-yl)pyr

R 1656; R-1656; R1656; PSI6130; PSI 6130

2'-deoxy-2'-fluoro-2'-C-methylcytidine

PSI 6130

R 1656

ethyl 4-broMo-1-Methyl-1H-pyrrole-2-carboxylate

ethyl 4-broMo-1-Methyl-pyrrole-2-carboxylate

4-Amino-1-((2R,3R,4R,5R)-3-fluoro-4-hydroxy-5-(hydroxymethyl)-3-methyltetrahydrofuran-2-yl)pyrimi

4-AMino-1-((2R,3R,4R,5R)-3-fluoro-4-hydroxy-5-(hydroxyMethyl)-3-Methyltetrahydrofuran-2-yl)pyriMidin-2(1H)-one

2'-deoxy-2'-fluoro-2'-C-methylcytidin

2'-Deoxy-2'-F-2'-C-methylcytidine

CS-1995

PSI-6130;PSI 6130

Cytidine, 2'-deoxy-2'-fluoro-2'-methyl-, (2'R)-

2'-deoxy-2'-fluoro-2'-C-methylcytidine,817204-33-4

2'-deoxy-2'-Fluoro-2'-methylcytidine

4-Amino-1-((2R,3R,4R,5R)-3-fluoro-4-hydroxy-5-(hydroxymethyl)-3-methyltetrahydrofuran-2-yl)pyrimidin-2(1H)-one (sofosbuvir Impurity)

Sofosbuvir Impurity 121

2'-C-methyl-2'-Fluoro-2'-deoxyCytidine

2'-Deoxy-2'-fluoro-2'-C-methylcytidine

817204-33-4

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